Detalhe da pesquisa
1.
The Translational Landscape of the Human Heart.
Cell
; 178(1): 242-260.e29, 2019 06 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-31155234
2.
A high-resolution map of human RNA translation.
Mol Cell
; 82(15): 2885-2899.e8, 2022 08 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35841888
3.
Inhibition of IL11 Signaling Reduces Aortic Pathology in Murine Marfan Syndrome.
Circ Res
; 130(5): 728-740, 2022 03 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35135328
4.
Nonspecific Inhibition of IL6 Family Cytokine Signalling by Soluble gp130.
Int J Mol Sci
; 25(3)2024 Jan 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38338642
5.
Interleukin-11 drives human and mouse alcohol-related liver disease.
Gut
; 72(1): 168-179, 2023 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35365572
6.
IL-11 is a crucial determinant of cardiovascular fibrosis.
Nature
; 552(7683): 110-115, 2017 12 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29160304
7.
A Neutralizing IL-11 Antibody Improves Renal Function and Increases Lifespan in a Mouse Model of Alport Syndrome.
J Am Soc Nephrol
; 33(4): 718-730, 2022 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-35140116
8.
Cardiomyocyte-Restricted Expression of IL11 Causes Cardiac Fibrosis, Inflammation, and Dysfunction.
Int J Mol Sci
; 24(16)2023 Aug 20.
Artigo
em Inglês
| MEDLINE | ID: mdl-37629170
9.
Vitamin B12 and folate decrease inflammation and fibrosis in NASH by preventing syntaxin 17 homocysteinylation.
J Hepatol
; 77(5): 1246-1255, 2022 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-35820507
10.
IL11 Stimulates IL33 Expression and Proinflammatory Fibroblast Activation across Tissues.
Int J Mol Sci
; 23(16)2022 Aug 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36012165
11.
IL11 Activates Pancreatic Stellate Cells and Causes Pancreatic Inflammation, Fibrosis and Atrophy in a Mouse Model of Pancreatitis.
Int J Mol Sci
; 23(7)2022 Mar 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-35408908
12.
Hepatocyte Specific gp130 Signalling Underlies APAP Induced Liver Injury.
Int J Mol Sci
; 23(13)2022 Jun 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-35806094
13.
IL11 is elevated in systemic sclerosis and IL11-dependent ERK signalling underlies TGFß-mediated activation of dermal fibroblasts.
Rheumatology (Oxford)
; 60(12): 5820-5826, 2021 12 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-33590875
14.
Fibroblast-specific IL11 signaling drives chronic inflammation in murine fibrotic lung disease.
FASEB J
; 34(9): 11802-11815, 2020 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-32656894
15.
Antibody-mediated neutralization of IL11 signalling reduces ERK activation and cardiac fibrosis in a mouse model of severe pressure overload.
Clin Exp Pharmacol Physiol
; 48(4): 605-613, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33462828
16.
Widespread Translational Control of Fibrosis in the Human Heart by RNA-Binding Proteins.
Circulation
; 140(11): 937-951, 2019 09 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-31284728
17.
Inhibiting Interleukin 11 Signaling Reduces Hepatocyte Death and Liver Fibrosis, Inflammation, and Steatosis in Mouse Models of Nonalcoholic Steatohepatitis.
Gastroenterology
; 157(3): 777-792.e14, 2019 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-31078624
18.
The Pathobiology of IL-11 in Kidney Disease: From Epithelial Cell to Fibroblast and Back Again.
Am J Pathol
; 193(12): 1910-1913, 2023 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-37816442
19.
IL11 stimulates ERK/P90RSK to inhibit LKB1/AMPK and activate mTOR initiating a mesenchymal program in stromal, epithelial, and cancer cells.
iScience
; 25(8): 104806, 2022 Aug 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35992082
20.
Spermidine-mediated hypusination of translation factor EIF5A improves mitochondrial fatty acid oxidation and prevents non-alcoholic steatohepatitis progression.
Nat Commun
; 13(1): 5202, 2022 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36057633